LHH-150GSD-UV Series Combined Pharmaceutical Photostability Test Chamber

Application Overview

Yiheng’s combined pharmaceutical photostability test chamber (with UV monitoring and control) adds visible-light and ultraviolet monitoring and control to the original GSD/GSP/GP combined stability test chambers. It is essential equipment for GMP certification in pharmaceutical and cosmetics companies and meets the photostability testing conditions of the ICH guidelines.
It scientifically establishes long-term stable temperature, humidity and lighting conditions for drug shelf-life evaluation. Suitable for accelerated, long-term, high-humidity and intense-light exposure tests of medicines and new drugs in pharmaceutical companies, it provides a reliable solution for pharmaceutical stability testing.

Product Features

Lighting System of the Combined Pharmaceutical Photostability Test Chamber

• The lighting system meets the lCH Q1B photostability testing requirements for new drug substances and products and corresponding international manufacturing standards, as well as the 2020 Pharmacopoeia guidelines for pharmaceutical stability testing. It scientifically simulates the long-term stable temperature, humidity and photostability environment needed to evaluate drug shelf life. It meets pharmaceutical companies’ temperature, humidity and photostability testing requirements for new drug substances and products;
• Shelf-mounted or outer-door lighting can be selected, including visible-light and UV lamps controlled independently. Single- or double-tier visible-light or UV lamps can be selected, and the sample shelf height in the chamber is adjustable (double-tier downward lighting system optional).

Irradiance Display, Monitoring and Control

• Overcomes the inability of existing pharmaceutical stability chambers to display and monitor irradiance, reducing stability-test errors caused by irradiance decay as visible-light and UV lamps age. Light intensity can also be adjusted continuously to meet test requirements. Visible-light and UV measurement probes with optical sensors, and an irradiance monitor certified by a third party, are provided for convenient observation and calibration;

Specialized UV Lamps

• Specialized UV lamps meet the ICH Q1B photostability testing requirements for new drug substances and products. Compared with other UV lamps, they provide stable quality and uniform spectral power. Their spectral power distribution does not decline as the lamps age, allowing more repeatable test results;
• UV lamp holders suitable for high-humidity operation;

User-Friendly Design

• New CFC-free design: high efficiency and low energy consumption promote energy savings and keep you at the forefront of healthy living;
• A microcomputer controller provides stable, accurate, reliable control. The 304 stainless-steel chamber has rounded corners for easy cleaning and convenient operation.
• Air-duct circulation ensures uniform airflow distribution in the chamber;
• A 25mm-diameter test port is standard on the left side;

Continuous Operation

• Two imported compressors switch automatically to ensure prolonged continuous pharmaceutical testing without faults, overcoming the limitation of domestically produced pharmaceutical test chambers that cannot operate continuously for extended periods;
• Continuous operation requires no defrosting, avoiding chamber temperature and humidity fluctuations caused by defrosting during use;

Quality Assurance

• Key components, including the temperature/humidity controller, compressors and circulating fan, are imported for stable, safe, reliable continuous operation over extended periods;

Imported Humidity Sensor

• A humidity sensor suitable for high-temperature operation avoids frequent replacement of wet-bulb wicks;

Programmable Touchscreen Controller (Standard on the “GSP” Series)

• The large touchscreen is easy to operate and program;
• Chinese and English controller interfaces are selectable, and real-time operating curves can be displayed on the screen;
• Capacity for 100 program groups, 1000 segments and 999 cycle steps, with a maximum time setting of 99 hours 59 minutes per segment;
• After data and test conditions are entered, screen locking prevents shutdown caused by accidental touch;
• P.I.D automatic calculation immediately corrects temperature and humidity change conditions for more precise, stable control;
• An RS-232 or RS-485 communication interface allows programs to be designed on a computer, testing to be monitored, and start-up, shutdown and other functions to be performed;

Recording and Fault-diagnosis Display

• If the test chamber develops a fault, the dynamic display shows clear operating fault information;
• A printer or 485 communication interface can be connected to record temperature and time curves using a computer and printer, supporting storage and playback of experimental data;

Wireless Alarm System (SMS Alarm System) — Optional

• If the equipment user is away when a fault occurs, the system promptly collects fault signals and sends an SMS to the designated recipient’s mobile phone. This supports prompt fault correction and resumption of testing, preventing losses;

Safety Functions

• An independent temperature-limit alarm system provides audible and visual warnings, ensuring safe experiments without accidents;
• Low-temperature, high-temperature and overtemperature alarms, plus high- and low-humidity alarms;
• A lockable door is standard to prevent accidental opening during tests and UV injury to laboratory personnel;

Technical Specifications